Is the Mattress Encasement hypoallergenic? December 12, 2023 17:48 Yes, both our mattress encasements and mattress protectors are designed to be hypoallergenic. Related articles What is the difference between a mattress encasement and a protector? Is the Down Alternative Pillow hypoallergenic? What's inside the Leesa Original Mattress? Why do you need a mattress protector? Is the Premium Latex Pillow hypoallergenic?